ABSTRACT
Corneal perforation is a potentially devastating complication that can result from numerous conditions that precipitate corneal melting. It is associated with significant morbidity and prompt intervention is necessary to prevent further complications. Causes include microbial keratitis, ocular surface disease, and autoimmune disorders and trauma. Various management options have been described in the literature to facilitate visual rehabilitation. This rview discusses the treatment options that range from temporising measures such as corneal gluing through to corneal transplantation, with decision making guided by the location, size, and underlying aetiology of the perforation.
ABSTRACT
We present a series of three patients with previously undetected corneal pathology in grafted corneal tissue following keratoplasty for keratoconus. Postoperatively, a faint layer of anterior stromal haze involving the graft was observed in each patient upon slit lamp examination. Anterior segment optical coherence tomography (AS-OCT) confirmed the presence of anterior stromal scarring across the transplanted cornea. However, the ocular and systemic medical histories of the donors were unremarkable. As the suboptimal donor corneal tissue may escape the standard screening protocols, eye banks should consider adding AS-OCT imaging for screening donor corneal tissue before transplantation.